Problem when using Spyder

Hi

I am new learning PyQt5 and Just bought the book and video, Thanks Martin.

I am using Spyder in anaconda, when running the code the first time, I have Qt windows pop up. After closing it, I cannot run the code anymore. I keep running it but no response at all. so I have exit Spyder and relaunch it in order to run the code. Why? anyone here can help me with it? Thanks

Thanks I solved it by run->profile.